By Muliere P., Petrone S.
His paper seems at a brand new method of the matter of discovering the maximal tolerated dose (or optimum dose, Eichhorn and Zacks, 1973) of definite medications which as well as their healing results have secondary damaging effects.The challenge is investigated in a sequential environment from a Bayesian predictive strategy. seek methods are proposed for parametric and nonparametric versions.
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Extra info for A bayesian predictive approach to sequential search for an optimal dose: Parametric and nonparametric
Essentially Benét sees the meaning of the war as Lincoln saw it: the war results in “a new birth of freedom,” a redeemed nation, a re-unified people. From our perspective in the twenty-first century, it is easy to forget how important such an attitude toward the War was, even in 1928. The divisiveness spawned by the War was bitter, deeply recriminatory, and enduring. In order to read the War as producing the kind of reconciliation he proposes, however, Benét emphasizes certain romantic, even sentimental elements and marginalizes certain troubling questions, and these aspects of his poem lend a peculiar shape to its “containing” of the war’s history.
55. Quoted in Stern, Varieties, 201. 56. , volume 2, ed. David Hollinger and Charles Capper, (New York: Oxford University Press, 2011), 548. 57. Quoted in Emery Neff, The Poetry of History (New York: Columbia University Press, 1947), 190. 58. Stern, Varieties, 318. 59. Arnaldo Momigliano, “The Introduction of History as an Academic Subject and Its Implications,” in The Golden and the Brazen World: Papers in Literature and History, 1650–1800, ed. John M. Wallace (Berkeley: University of California Press, 1985), 203.
53 They believe that the past is knowable, and that history affords methods by which more valid accounts of the past may be distinguished from less valid accounts. Still, they assert that “All histories are provisional. None will have the last word,” 54 an idea that reaches back in American history at least as far as Frederick Jackson Turner, who in “The Significance of History” wrote: “The first lesson the student of history has to learn is to discard his conception that there are standard 16 Chapter 1 ultimate histories.